The Impact of The COVID-19 Pandemic On SLE.

Little is known about the association between coronavirus disease 2019 [COVID-19] and autoimmune diseases, especially for systemic lupus erythematosus [SLE]. SLE patients meet with a throng of questions during the pandemic, including minimize the risk of infection, the complex pathological features and cytokine profiles, diagnosis and treatment, rational choice of drugs and vaccine, good nursing and psychological supervision, etc. In this study, we review and discuss the multifaceted effects of the COVID-19 pandemic on patients living with SLE using the available literatures. Cross-talk was existed in implicated inflammatory pathways/mechanisms between SLE and SARS-CoV-2 infection, and SARS-CoV-2 infection shares similarities with SLE in clinical characters and immuno-inflammatory responses. Current epidemiological data inadequate assess the risk and severity of COVID-19 in SLE. More evidences supported that HCQ and CQ unable prevent COVID-19. During the pandemic, patients with SLE had a higher rate of hospitalization. Vaccination helps to reduce the risk of infection. Several therapies for patients with SLE infected COVID-19 were discussed. The cases in the study can provide meaningful information for clinical diagnosis and management. Our mainly aim is to help the prevention and treatment of patients with SLE infected COVID-19.

College Students' Degree of Support for Online Learning during the COVID-19 Pandemic and Associated Factors: A Cross-Sectional Study.

BACKGROUND: Educational institutions worldwide have experienced the suspension of offline teaching activities in favor of online teaching due to the outbreak of the COVID-19 pandemic. However, few studies have focused on the degree of support for online learning among college students in mainland China. Therefore, the aim of this study was to investigate the degree of support for online learning among Chinese college students during the epidemic and whether depression, loneliness, family communication, and social support were associated factors. METHODS: A questionnaire was used to collect cross-sectional data from 9319 college students in mainland China, and a structural equation model was analyzed. RESULTS: The results of the study showed high degrees of support for online learning among Chinese college students during the COVID-19 pandemic, with more than half expressing support. The SEM (Structural Equation Modeling) results showed that depression had a negative and significant effect on college students' support for online learning (ß = -0.07; p < 0.001); family communication had a positive and significant effect on college students' support for online learning (ß = 0.09; p < 0.001); social support had a positive and significant effect on college students' support for online learning (ß = 0.11; p < 0.001). CONCLUSIONS: Social support and family communication can alleviate the negative psychological status of college students, and depression plays a mediating role in the effect of social support and family communication on college students' degree of support for online learning. In addition, a significant chain-mediating effect was found of family communication, loneliness, and depression between social support and college students' degree of support for online learning. Government and education institutions must focus on college students' mental health issues and consider family interventions and general support that college students require.

COVID-19 impact on the Chinese top academic libraries: Libraries' response to space, collection and services.

In 2020, the COVID-19 pandemic was a major public health emergency on a global scale. The literature regarding the pandemic and its impact on academic libraries is still rising. This article examines the two-year process of developing a flexible service scenario and the broader picture by analyzing data on Chinese top university libraries' programmes and outreach initiatives prior to, during, and the normal COVID-19 pandemic (Sept. 2019-Sept. 2021). COVID-19 is found to have a significant impact on the physical space, collection development, and service of the library, demonstrating the characteristics of space access restricted by security measures, collection digitization, and online service. This research also examines the previous year's initiatives and programmes and discusses the next phase of "new normal" procedures. Hopefully, this study will give insight on how Chinese libraries responded to the recent pandemic, informing libraries' outreach and efforts to be better prepared to take imperative, swift, and decisive action in the post-COVID-19 era and beyond.

Dynamics of an SIR epidemic model incorporating time delay and convex incidence rate

In this paper, dynamical behaviors including stability and Hopf bifurcation of a delayed SIR epidemic model with convex incidence rate are examined. We first discuss the existence of Hopf bifurcation. Subsequently, direction and stability of Hopf bifurcation are investigated. Moreover, length of the time delay which can retain stability of the proposed model has been appraised. Specially, global exponential stability is studied. Finally, numerical simulations are carried out with the suitable choices of parameters in the prosed model.